What is a GLP-1? A Smart Girl’s Guide to Semaglutide & Tirzepatide

what is a glp-1?

Hey gorgeous humans! đź‘‹ So you’ve probably been hearing “GLP-1” thrown around like it’s the hottest new skincare ingredient (spoiler: it’s not for your face, bestie). But seriously, what is a GLP-1 and why is literally everyone talking about it? Whether you’re scrolling through #ozempiccheck TikToks or your bestie just started her “journey,” I’m here to break down everything you need to know about this game-changing GLP-1 medication without the medical jargon that makes your brain go brrr.

Let’s dive into the world of GLP-1 receptor agonists – aka the medications that are having their main character moment right now.

What is a GLP-1 and How Do the Medications Work?

what are GLP-1s

Okay, time for some science that’s actually interesting! What is a GLP-1 and how do they work? GLP-1 mechanism of action is basically your body’s internal “I’m full, thanks” signal getting a major upgrade.

GLP-1 (glucagon-like peptide-1, if you’re fancy) is a hormone your intestines naturally produce when you eat. Think of it as your body’s personal food coach – it tells your brain “hey girl, we’re good on food” and slows down how fast your stomach empties. It’s like having a bestie who reminds you that you don’t actually need that third slice of pizza (but in a nice way, not judgy).

GLP-1 receptor agonists are synthetic versions that work WAY longer than your natural GLP-1. While your body’s version lasts about 2 minutes (literally shorter than a TikTok), these medications stick around for hours or even a whole week. They’re basically the long-lasting lip stain of hormones.

The GLP-1 vs GIP situation gets spicy here too – some medications target both receptors for double the impact. More on that drama later! But that’s the gist of “what is a GLP-1”.

GLP-1 for Weight Loss: Why It’s Trending

Let’s be real – GLP-1 for weight loss became the main character because it actually works, and we love to see it. These medications don’t just make you less hungry; they literally change your relationship with food.

Users report:

  • Feeling satisfied with smaller portions (revolutionary, I know)
  • Less food noise (goodbye, 2 AM snack attacks)
  • Slower eating (mindful queen energy)
  • Reduced cravings for processed foods

The science is solid too – clinical trials show 15-20% weight loss on average. That’s not just “I lost 5 pounds and gained it back” territory; that’s life-changing results that stick around.

So now that we’ve answer the main question, “What is a GLP-1?”, here’s the tea: this isn’t a quick fix or magic pill situation. GLP-1 medication works best when paired with lifestyle changes. Think of it as your supportive bestie, not your fairy godmother.

Semaglutide vs Tirzepatide: What’s the Difference?

semaglutide vs tirzepatide

Time for the ultimate face-off! Your question “what is a GLP-1?” has been answered, now let me ask you a question – Semaglutide (Ozempic, Wegovy) vs tirzepatide (Mounjaro, Zepbound), which team are you on?

Semaglutide is the OG that started this whole conversation:

  • Targets GLP-1 receptors only
  • Weekly injection
  • Ozempic for diabetes, Wegovy for weight loss (same drug, different doses)
  • Been around longer = more data

Tirzepatide is the newer kid with extra tricks:

  • Targets both GLP-1 AND GIP receptors (overachiever energy)
  • Weekly injection
  • Mounjaro for diabetes, Zepbound for weight loss
  • Potentially more weight loss in studies

The GLP-1 vs GIP combo in tirzepatide is like having two hormones working together instead of just one. GIP helps with insulin and might boost the weight loss effects. It’s giving power couple vibes.

Which one’s better? Honestly, it depends on your body, your goals, and how you respond. Some people are semaglutide girlies, others are team tirzepatide. Both are valid!

Are GLP-1s Safe?

are GLP-1s safe?

The safety question – because we’re not about that risky business life. It’s not enough to answer “what is a GLP-1?” without answering ” are they safe?”. GLP-1 receptor agonists have been used for diabetes for over a decade, so we have solid long-term data.

Most common side effects are digestive (nausea, some bathroom drama) and usually improve as your body adjusts. The key is starting slow and listening to your body. You can also get ahead of the game and check out our GLP-1 Survival Kit post that lays out what supplements can help you if you do encounter some side effects or avoid them altogether!

Red flags to discuss with your doctor:

  • History of thyroid issues
  • Pancreatitis
  • Severe digestive problems
  • Eating disorders

Always, ALWAYS work with a healthcare provider who knows their stuff. This isn’t a DIY situation, babes.

Where to Get GLP-1s Online

where to get GLP-1s

Okay so we’ve answered the “What is a GLP-1?” question and it sounds like it’s just what you’ve been looking for. Are you ready to start your journey? Here’s where to find legit GLP-1 medications:

GobyMeds offers comprehensive telehealth consultations with experienced providers who specialize in weight management. They handle everything from consultation to prescription delivery. They currently offer both semaglutide, tirzepatide, and other peptide therapy like sermorelin and NAD. You are able to place orders on a month to month basis or bulk orders (of the GLP-1s) of up to 3 months at once! Sign-up form is here.

gobymeds banner

OrderlyMeds provides another reliable option for accessing GLP-1 medications through licensed healthcare providers, with competitive pricing and excellent customer support. They are the go-to for people new to GLP-1s because their SimpleStart program, which is like a 3 month starter kit, is only $249! We’ve been in the game for a long time and that is THE most affordable way to get started on a GLP-1 from a legit, reliable provider. Imagine what kind of transformation you can get in just 3 months?! Sign-up form is here. If your curious about the sign-up process, we’ve also done a walkthrough that you can find here!

orderlymeds banner

Both platforms ensure you’re getting genuine medication with proper medical oversight – because sketchy internet drugs are not it, bestie.

Best GLP-1 Support Tools

Your GLP-1 medication journey deserves the best support squad! Here are my favorite Amazon finds:

best GLP-1 support tools

Organization Queens:

Hydration Heroes:

  • Large water bottles with time markers (staying hydrated is crucial: link here)
  • Electrolyte packets for those rough days (amazon link)

Protein Power-Ups:

Kitchen MVPs:

The Bottom Line

So what is a GLP-1? It’s a hormone that became a medication that’s changing lives – and honestly, we love that for everyone finding success with it.

Whether you’re team semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound), the most important thing is working with qualified healthcare providers and supporting your journey with sustainable lifestyle changes.

Remember: you’re not broken, you don’t lack willpower, and if GLP-1 for weight loss helps you feel healthier and happier, that’s what matters. Do your research, ask questions, and make the choice that’s right for YOUR body.

Now go forth and make informed decisions like the smart, empowered human you are! đź’Ş

 DISCLAIMER: Some links on this site are affiliate links, which means we might earn a small commission if you shop through them (no extra cost to you—think of it as buying us a matcha 🍵 for the research).
While some of us are doctors, we’re not your doctors. The info on this site is meant to educate and empower, not diagnose or treat. Always chat with your own healthcare provider before starting new meds, peptides, supplements, or that intense cold plunge-fasting-stack we’re raving about. You do you—but do it safely. 💪

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